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Important Days
World Cotton Day β October 7
Initiated by Cotton-4 nations (Benin, Burkina Faso, Chad, Mali). First celebrated on 7 Oct 2019 at WTO. UN officially recognized it on 30 Aug 2021. Involves FAO, UNCTAD, ITC, and ICAC.
Governance
Free Aadhaar Biometric Updates
UIDAI waived charges for Mandatory Biometric Updates (MBU) for children aged 5β17 years for one year from 1 Oct 2025. Updates required at ages 5 and 15 for accessing education benefits, scholarships, and DBT.
Women Empowerment
Coal India’s All-Women Store Unit
First all-women operated Central Store Unit at SECL’s Central Workshop, Korba. Managed by 8 women officers led by Ms. Sapna Ikka (IIT-ISM Dhanbad). Uses SAP-based digital inventory.
Infrastructure
World’s Highest Motorable Road
BRO built road at Mig La Pass, Ladakh β 19,400 ft, breaking previous record of Umling La (19,024 ft). Part of LikaruβMig LaβFukche alignment under Project Himank.
Environment
Namo Biodiversity Park (NAMO VAN)
Rajasthan’s first NAMO VAN inaugurated at Pratap Bandh, Alwar on 5 Oct 2025 by Union Environment Minister. Serves as a green lung promoting biodiversity and environmental awareness.
Cryptocurrency
Bitcoin Crosses $125,000
Bitcoin peaked at ~$125,245.57. Driven by institutional demand, ETF inflows, supportive U.S. regulations, and a weaker dollar amid government shutdown concerns.
Business
Maruti Suzuki Navratri Sales Record
Maruti Suzuki delivered 165,000 vehicles in first 8 days of Navratri 2025, including 30,000 on Day 1 β best single-day sales in 35 years. Boosted by GST rationalisation.
Nobel Prize
2025 Nobel Prize in Physiology/Medicine
Awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for discovery of Regulatory T cells (Tregs) and Foxp3 gene underpinning peripheral immune tolerance. Applications in autoimmunity and cancer therapy.
Skill Development
PM SETU Scheme
Launched on 4 Oct 2025 to modernize 1,000 ITIs with βΉ60,000 crore outlay. Five National Centers of Excellence at Ludhiana, Kanpur, Bhubaneswar, Hyderabad, Chennai.
Space
Vyommitra β Gaganyaan Mission
Vyommitra is ISRO’s semi-humanoid that simulates human presence during uncrewed test flights. Can communicate in English/Hindi, operate control panels, and monitor spacecraft systems before India’s 2027 crewed mission.
π΄ Revision Flashcards
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Tap to Reveal
Which countries initiated World Cotton Day?
Cotton-4: Benin, Burkina Faso, Chad, Mali
Observed on October 7
Tap to Reveal
What is the world’s highest motorable road (2025)?
Mig La Pass, Ladakh β 19,400 ft
Built by BRO under Project Himank
Tap to Reveal
What discovery won 2025 Nobel Prize in Medicine?
Regulatory T cells (Tregs) and Foxp3 gene
For peripheral immune tolerance
Tap to Reveal
How many ITIs will PM SETU scheme modernize?
1,000 ITIs
βΉ60,000 crore outlay; 5 Centers of Excellence
Tap to Reveal
What is Vyommitra in Gaganyaan mission?
Semi-humanoid for uncrewed test flights
Simulates human presence; speaks English/Hindi
Tap to Reveal
Where is Coal India’s first all-women store unit?
SECL’s Central Workshop, Korba
Led by Ms. Sapna Ikka; SAP-based system
Tap to Reveal
Where is Rajasthan’s first NAMO Biodiversity Park?
Pratap Bandh, Alwar
Inaugurated on 5 Oct 2025
Tap to Reveal
Maruti Suzuki’s Day 1 Navratri 2025 deliveries?
30,000 vehicles
Best single-day sales in 35 years
Think & Discuss
Regulatory T Cells: A New Frontier in Medicine
Context from today’s quiz: The 2025 Nobel Prize in Physiology or Medicine was awarded for the discovery of Regulatory T cells (Tregs) and the Foxp3 gene, which explain how the immune system avoids attacking the body’s own tissues. This breakthrough has profound implications for treating autoimmune diseases, cancer, and improving organ transplant outcomes.
π€ Your Perspective Matters
The discovery of Tregs represents a paradigm shift in immunology. Instead of just boosting immune response, we now understand how to modulate it. This opens doors to treating conditions from Type 1 Diabetes to Multiple Sclerosis by restoring immune tolerance rather than suppressing the entire immune system.
How might Treg-based therapies transform the treatment of autoimmune diseases and cancer immunotherapy in the coming decade?
How might Treg-based therapies transform the treatment of autoimmune diseases and cancer immunotherapy in the coming decade?
- Could personalized Treg therapy eventually replace lifelong immunosuppressive drugs for autoimmune patients?
- How can India leverage this discovery to develop affordable immunotherapies for its population?
- What ethical considerations arise when manipulating the immune system at such a fundamental level?
We’d love to hear your thoughts! Share your perspective in the comments.
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