GK One Liners: November 10, 2025

NexCAR19 & CAR (Chimeric Antigen Receptor) T-Cell Therapy What it is: CAR T-cell therapy is an advanced immunotherapy in which a patient’s own T lymphocytes are genetically modified to express chimeric antigen receptors, enabling them to recognise and destroy specific cancer cells.
NexCAR19: India’s first indigenous CAR T-cell product, developed by ImmunoACT with IIT Bombay and Tata Memorial Hospital, targets B-cell blood cancers.
Significance: It reduces dependence on extremely costly imported therapies and makes personalised oncology more accessible in India.

U.N. Water Convention — Transboundary Focus Full name: Convention on the Protection and Use of Transboundary Watercourses and International Lakes, adopted in Helsinki in 1992 under the United Nations Economic Commission for Europe (UNECE).
Core idea: Promote cooperation, information-sharing, and joint management of rivers, lakes, and aquifers that cross borders, reducing conflict and environmental damage.
Bangladesh’s move: As the first South Asian party, it gains a rules-based platform for managing shared waters with neighbours and strengthening climate-resilient water governance.

SBI’s Scale: Market Cap & Total Business SBI (State Bank of India): India’s largest commercial bank by assets and branch network.
Market cap milestone: A $100 billion valuation reflects strong investor confidence, profitability, and balance-sheet strength.
Total business of ₹100 trillion: Refers to the combined value of deposits mobilised and loans (advances) extended, capturing SBI’s reach in retail, corporate, and rural banking.
Why it matters: Together, these figures underline SBI’s systemic importance to India’s financial system and credit growth.